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Guide · GLP-1 clinics

Before You Pay an Online GLP-1 Clinic: A Practical Checklist

The time to check an online GLP-1 clinic is before you enter card details, not after the first charge. These 14 checks explain why each one matters and how to verify it yourself, using free public tools from FDA, state licensing boards and other official sources. None of them requires medical knowledge.

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Key takeaways

  • Verify two licenses: the prescriber's (state medical or nursing board) and the pharmacy's (state board of pharmacy).
  • Know whether you are paying for an FDA-approved or a compounded drug; compounded drugs are not FDA-approved, and FDA does not review them for safety, effectiveness or quality before marketing.
  • Write down the recurring charge, the billing interval, the price at higher doses and the cancellation deadline before you pay.
  • The FTC's 2024 click-to-cancel rule was vacated in July 2025, but the federal ROSCA law still requires simple ways to stop recurring online charges.
  • Report side effects or product problems to FDA's MedWatch program, and read BBB and Trustpilot profiles for patterns, not just the star rating.
On this page10 sections
  1. Start with FDA's telehealth red flags
  2. Who is treating you (checks 1–3)
  3. What you are buying (check 4)
  4. What it costs and how you leave (checks 5–8)
  5. Care after checkout (checks 9–11)
  6. Trust signals and privacy (checks 12–14)
  7. Keep a one-page record
  8. FAQ
  9. Keep reading
  10. Sources

Start with FDA's telehealth red flags

FDA lists warning signs for people buying GLP-1 drugs through telehealth. In summary, watch for a company that:

  • claims a compounded drug is the same as an FDA-approved drug;
  • offers “deep discounts or prices that seem too good to be true”;
  • sends medicine that looks different from what you received before or from what its website showed, or that arrives damaged or without instructions for use;
  • does not require a screening and prescription by a licensed doctor before providing medicine;
  • has no licensed doctor available to answer questions after your medication arrives;
  • uses labels with spelling errors or incorrect pharmacy addresses, or names a pharmacy you suspect is fraudulent.

Any of these is a reason to get answers before you pay.

Who is treating you (checks 1–3)

1. The clinician’s license, in your state

Why it matters: HHS says health professionals must be “licensed or legally permitted to practice in the state where the patient is located.”

How to verify: Ask for the prescriber’s full name and credentials. State medical board profiles include at least “licensure status and disciplinary history,” according to the Federation of State Medical Boards (FSMB), whose free DocInfo database adds license history, medical school and specialty. For nurse practitioners, use your state board of nursing or NCSBN’s free Nursys QuickConfirm service; Nursys covers “RNs, LPN/VNs and APRNs” from participating boards.

2. Who actually prescribes and supplies the drug

Why it matters: The brand on the website may not be the company that compounds your medication. FDA’s March 3, 2026 warning letters to 30 telehealth companies cited “obscuring product sourcing” through branding that implied the telehealth firm was the compounder.

How to verify: Find the medical group’s legal name in the terms of service or consent forms, and confirm that a licensed clinician reviews your health information before anything is prescribed. FDA treats skipping “a screening and prescription by a licensed doctor” as a red flag.

3. The pharmacy’s name and license

Why it matters: FDA says patients should “fill the prescription at a state-licensed pharmacy.” A pharmacy the clinic will not name is a pharmacy you cannot check.

How to verify: Get the pharmacy’s legal name and state, then search the state license databases linked from FDA’s BeSafeRx page. FDA’s rule of thumb: “If your online pharmacy is not listed, you should not use that pharmacy.” For a claimed 503B outsourcing facility, check FDA’s registered outsourcing facility list. Our guide to 503A vs 503B pharmacies explains the difference.

What you are buying (check 4)

4. FDA-approved or compounded

Why it matters: Compounded drugs are not FDA-approved, which FDA says means the agency “does not review their safety, effectiveness or quality before they are marketed.” They are not generics either, and FDA says companies cannot claim compounded products are generic versions of, or the same as, FDA-approved drugs, or “clinically proven to produce results for the patient.”

How to verify: Ask for the exact product and who makes or compounds it. FDA-approved brand-name and generic prescription drugs are listed in Drugs@FDA. Drugs from 503B outsourcing facilities must carry the label statement “This is a compounded drug.” Treat “same as,” “generic” or “FDA-approved pharmacy” wording as a reason to ask more: FDA says it “does not approve or license any facility.”

What it costs and how you leave (checks 5–8)

5. The full recurring charge and the billing interval

Why it matters: A price shown “per month” may reflect a calendar month, a shorter billing cycle or a prepaid plan divided by 12. A plan billed every four weeks, for example, charges 13 times a year, not 12 (our calculation: 52 weeks ÷ 4 = 13 charges).

How to verify: Before entering card details, note each recurring amount, how often it repeats, what it includes and any separate fees, and screenshot the checkout page. The federal Restore Online Shoppers’ Confidence Act (ROSCA) requires online sellers of automatically renewing plans to disclose “all material terms of the transaction before obtaining the consumer’s billing information.”

6. Whether the price changes with the dose

Why it matters: An introductory price may not apply to every dose or every month. If a clinic charges more for higher doses, your cost can rise as your prescription changes.

How to verify: Ask in writing whether the price is the same at every dose, when any introductory discount ends and what you will pay after that, and keep the reply. Our review criteria include whether a clinic says its price is the same at every dose.

7. What happens if a clinician declines you

Why it matters: If a clinic takes payment before a clinician reviews your intake, its refund rule decides what happens to your money when treatment is not prescribed.

How to verify: Find the sentence in the refund policy that covers declined or ineligible patients. Check whether the refund is full and automatic, how long it takes and whether consultation or intake fees are excluded.

8. Refunds, cancellation and auto-renewal

Why it matters: These terms decide what you pay if you stop: when a cancellation takes effect and whether prepaid months are refundable.

How to verify: Find the cancellation deadline before each billing date, the ways to cancel, whether shipped medication is refundable and whether any advertised guarantee appears in the policy itself. Save a copy of the terms.

Federal rules in 2026: The FTC’s 2024 “click-to-cancel” rule was vacated by the U.S. Court of Appeals for the Eighth Circuit on July 8, 2025. The FTC restored the rule’s pre-2024 form on February 12, 2026 and asked for public comment on whether to amend it on March 11, 2026; its rule page listed no new rule as of September 16, 2026. ROSCA still requires sellers to obtain “express informed consent” and provide “simple mechanisms for a consumer to stop recurring charges.”

Care after checkout (checks 9–11)

9. Labs and health screening

Why it matters: Screening is how a prescriber decides whether a medication fits your health history, and FDA lists skipping a screening by a licensed doctor among its telehealth red flags.

How to verify: Ask what the intake covers, whether lab work is required, who orders and pays for it and whether the clinician may ask for recent results.

10. Follow-up and dose adjustments

Why it matters: FDA flags a company that “does not have a licensed doctor available to answer questions after you receive your medication.” FDA has also reported dosing errors tied to confusion between milliliters, milligrams and “units.”

How to verify: Ask how often a clinician checks in, how to reach one in between, how quickly they reply and who decides on dose changes. FDA encourages patients to talk with their health care provider or compounder “about how to measure and administer the intended dose.”

11. Side-effect support and FDA MedWatch

Why it matters: Compounded GLP-1s are not FDA-approved, and as of May 31, 2026, FDA had received 990 adverse event reports associated with compounded semaglutide and more than 730 associated with compounded tirzepatide. FDA notes it is “not always possible to determine if the adverse event directly resulted from use of the drug.”

How to verify: Ask who answers side-effect questions, during which hours, and what the clinic tells patients to do in an urgent situation. Patients and consumers can report side effects or product problems to FDA’s MedWatch program online or on Form FDA 3500B; FDA’s information line is 1-888-INFO-FDA (1-888-463-6332).

Trust signals and privacy (checks 12–14)

12. LegitScript certification, checked at the source

Why it matters: LegitScript’s healthcare certification standards include licensure, validity of prescriptions, privacy and transparency.

How to verify: Rather than trusting a badge image, enter the clinic’s web address on LegitScript’s status page, which shows whether a site is “LegitScript-certified, legitimate, or rogue.” Certification does not replace the license checks above.

13. BBB and Trustpilot, read for patterns

Why it matters: The BBB calls its grade “BBB’s opinion of how a business is likely to interact with its customers” and says a rating “is not a guarantee.” Trustpilot says its rating “isn’t just a simple average”: newer reviews carry more weight, and seven neutral reviews are built into the calculation.

How to verify: On BBB, read complaint details and company responses; “NR” (no rating) is “not a grade,” BBB says. On Trustpilot, read recent one-star reviews for repeated themes such as billing, shipping or cancellation, and note whether the business has claimed its profile and responds to feedback. Trustpilot’s calculation does not distinguish between “verified, invited, or unprompted reviews.”

14. Privacy: what HIPAA does and does not cover

Why it matters: HIPAA applies to covered entities (health plans, health care clearinghouses and health care providers that conduct certain transactions electronically) and their business associates; HHS says other entities do not “have to comply with the HIPAA Rules.” The FTC’s Health Breach Notification Rule covers some businesses outside HIPAA, such as apps and websites that hold consumers’ health information, and requires breach notices to “affected consumers, the FTC, and, in some cases, the media.”

How to verify: Read the privacy policy and any notice of privacy practices: which company collects your information, which partners receive it and whether it is sold. FDA’s BeSafeRx campaign lists a pharmacy site that “does not provide clear written protections of your personal and financial information” as a warning sign.

Keep a one-page record

Before you pay, fill in a record like this and keep it with your screenshots.

ItemWhat to write down
PrescriberName, credentials, license state and number
Medical groupLegal name from the terms or consent form
PharmacyLegal name, state, license number, 503A or 503B
MedicationProduct name; FDA-approved or compounded
PriceRecurring amount, billing interval, price at higher doses
CancellationDeadline before each billing date and how to cancel
RefundsRule if a clinician declines you; rule after shipment
SupportHow to reach a clinician and the pharmacy

To see how individual clinics handle these points, browse our GLP-1 clinic reviews and read how we review them.

Frequently asked questions

How can I tell if an online GLP-1 clinic is legitimate?

Start with checks 1 to 3: a prescriber licensed in your state, a pharmacy licensed by a state board of pharmacy, and a screening before any prescription. Then compare the clinic with FDA’s telehealth red flags, such as prices that “seem too good to be true.”

Is compounded semaglutide or tirzepatide the same as the FDA-approved drug?

No. Compounded drugs are not FDA-approved, and FDA does not review them for safety, effectiveness or quality before they are marketed. FDA says companies cannot call them generic versions of, or the same as, FDA-approved drugs. FDA also says some compounded semaglutide may be a salt form, which is a different active ingredient from the one in the approved drugs.

Is the FTC's click-to-cancel rule in effect?

No. A federal appeals court vacated it on July 8, 2025. The FTC restored its earlier rule on February 12, 2026 and asked for comment on possible changes on March 11, 2026; its rule page listed no new rule as of September 16, 2026. ROSCA still requires express informed consent and simple ways to stop recurring online charges.

Does HIPAA protect everything I enter on a telehealth website?

Not necessarily. HIPAA applies to covered entities and their business associates, and HHS says other entities do not have to comply with the HIPAA Rules. The FTC’s Health Breach Notification Rule requires some non-HIPAA businesses, such as health apps and websites, to give notice after a breach.

What should I do if I have side effects?

Contact your prescriber, and seek emergency care for severe symptoms. FDA’s advice is: “Talk to your doctor if you have questions about your medicines.” You can also report the problem to FDA’s MedWatch program online or on Form FDA 3500B.

Are Trustpilot and BBB ratings reliable?

They are signals, not verdicts. BBB says a rating “is not a guarantee of a business’s reliability or performance,” and Trustpilot’s rating gives more weight to recent reviews. Read complaints and one-star reviews for repeated themes.

Upkeepwell Editorial

Research & comparison team

Upkeepwell compares online health programs by reading what each company publishes (prices, terms, refund and pharmacy disclosures) and its public records. Every program is checked against the same six criteria, every fact on the page is sourced, and no company pays us for a review or a ranking.

Sources26Facts on this page come from these sources, read on the dates shown.
  1. FDA: FDA's Concerns with Unapproved GLP-1 Drugs Used for Weight Lossfda.gov · read September 16, 2026
  2. FDA: Human Drug Compoundingfda.gov · read September 16, 2026
  3. FDA press announcement: FDA Intends to Take Action Against Non-FDA-Approved GLP-1 Drugs (February 6, 2026)fda.gov · read September 16, 2026
  4. FDA press announcement: FDA Warns 30 Telehealth Companies Against Illegal Marketing of Compounded GLP-1s (March 3, 2026)fda.gov · read September 16, 2026
  5. FDA: FDA to Telehealth Companies: What to Know When Promoting Compounded Drugsfda.gov · read September 16, 2026
  6. FDA: FD&C Act Provisions that Apply to Human Drug Compoundingfda.gov · read September 16, 2026
  7. FDA: FDA alerts health care providers, compounders and patients of dosing errors associated with compounded injectable semaglutide products (July 26, 2024)fda.gov · read September 16, 2026
  8. FDA: About Drugs@FDAfda.gov · read September 16, 2026
  9. FDA BeSafeRx: Locate a State-Licensed Online Pharmacyfda.gov · read September 16, 2026
  10. FDA BeSafeRx: Considering an Online Pharmacy?fda.gov · read September 16, 2026
  11. FDA: Registered Outsourcing Facilitiesfda.gov · read September 16, 2026
  12. FDA: Reporting Serious Problems to FDA (MedWatch)fda.gov · read September 16, 2026
  13. HHS Telehealth.HHS.gov: Getting started with licensuretelehealth.hhs.gov · read September 16, 2026
  14. Federation of State Medical Boards: Information for Consumers (DocInfo)fsmb.org · read September 16, 2026
  15. NCSBN: License Verification (Nursys.com)ncsbn.org · read September 16, 2026
  16. LegitScript: Healthcare Certificationlegitscript.com · read September 16, 2026
  17. LegitScript: Website Certification Statuslegitscript.com · read September 16, 2026
  18. BBB: Overview of BBB ratingsbbb.org · read September 16, 2026
  19. Trustpilot Help Center: TrustScore and star rating explainedhelp.trustpilot.com · read September 16, 2026
  20. HHS: Covered Entities and Business Associateshhs.gov · read September 16, 2026
  21. FTC: Health Breach Notification Rule: The Basics for Businessftc.gov · read September 16, 2026
  22. FTC: Restore Online Shoppers' Confidence Act (statute text)ftc.gov · read September 16, 2026
  23. U.S. Court of Appeals for the Eighth Circuit: Custom Communications, Inc. v. FTC, No. 24-3137 (July 8, 2025)ecf.ca8.uscourts.gov · read September 16, 2026
  24. Federal Register: Revision of the Negative Option Rule, Withdrawal of the CARS Rule, Removal of the Non-Compete Rule To Conform These Rules to Federal Court Decisions (February 12, 2026)federalregister.gov · read September 16, 2026
  25. FTC press release: FTC Seeks Public Comment in Response to Advance Notice of Proposed Rulemaking Regarding Negative Option Marketing Practices (March 11, 2026)ftc.gov · read September 16, 2026
  26. FTC: Negative Option Ruleftc.gov · read September 16, 2026
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