Sesame Review 2026: Menopause Care, Price Up Front

Sesame’s pitch is a number you see before you commit. Its telehealth visit page says it plainly: “See the price for your virtual visit before you book. No hidden fees or surprise bills.” Read September 18, 2026.

Sesame’s menopause page is headed “Online menopause treatment, tailored to you,” under the subheadline “Same-day treatment for perimenopause & menopause symptoms.” It lists hot flashes, night sweats, vaginal dryness, low libido, mood swings and hair loss; the May 2025 launch post adds insomnia and brain fog.

The hormone menu, named on the page

Unusually for a booking platform, Sesame prints the drug names. Estrogen is listed as estradiol — the generic of Estrace, Climara and Divigel — with the combinations Prempro, Bijuva and Mimvey. Progesterone appears as the generic of Prometrium and Crinone, and prasterone as Intrarosa.

Sesame names these as brand-name medicines or their generics, sent to a retail pharmacy. No Sesame page we read describes any of them as a compounded preparation, and we did not confirm each product’s approval status; you can look an exact product up in the FDA’s Orange Book. Nothing on the menopause page, or on Sesame’s estradiol, progesterone and Prempro pages, is described as a compounded preparation. That matters, because a compounded medicine is mixed for one patient and holds no approval: the FDA does not review such preparations for safety, effectiveness or quality before marketing.

Non-hormonal routes are named too — gabapentin, clonidine, ospemifene, paroxetine, sertraline and trazodone — with vitamin D, calcium, minoxidil, alendronate and risedronate as supportive items. Labs come with the first visit: “Basic lab work is included, if necessary,” described in the launch post as hormonal health, blood sugar, thyroid function and cholesterol, with no stand-alone price published.

One thing Sesame will not prescribe

Controlled substances are excluded platform-wide. Sesame’s prescription refill page states that providers “will not prescribe any medication listed as a controlled substance, including opioids, benzodiazepines, stimulants, testosterone, and narcotics.” Testosterone is sometimes prescribed off-label for low libido in midlife, so that is a real limit here. Every hormone Sesame does list is non-controlled, which is part of why it can reach a retail pharmacy the same day. Sesame’s progesterone page adds that “All prescriptions are at the discretion of the provider.”

Sesame is a marketplace: it lists clinicians, takes the booking and the payment, and the care comes from the clinician you picked. The Terms of Service say so in capitals — “SESAME DOES NOT PROVIDE ANY MEDICAL SERVICES NOR MEDICAL ADVICE” — and add “NO HEALTH CARE PROVIDER/ PATIENT RELATIONSHIP IS CREATED WHEN YOU USE THE SERVICES.”

In practice you book a licensed clinician directly rather than enrolling with a clinic. Sesame’s homepage states that “Sesame-affiliated provider practices are independently owned and operated by licensed clinicians who provide clinical services using the Sesame telehealth platform.” Your notes and your prescription sit with that clinician, and Sesame limits its own exposure on logistics: “Sesame is not liable for any cancelled or unfulfilled appointments, or any injury or loss resulting from the foregoing.”

Who is on the list. The menopause page shows more than 60 licensed clinicians — MDs, DOs, NPs, PAs, APRNs, DNPs and FNPs — and site-wide Sesame advertises “10K+ board-certified providers.” The vetting behind those numbers is not published, so read the clinician’s profile before booking.

Pharmacy. Here the marketplace model works in your favor. Sesame runs no captive pharmacy, so “your provider can send your progesterone prescription to the pharmacy of your choice,” and the estradiol page adds “options for same-day pickup when available.” A prescription filled at your usual counter is one your drug benefit can see, even though the visit is cash-pay.

Where. The telehealth page says “You can find licensed healthcare providers in all 50 states on Sesame, 24/7.” The Terms of Service put it more narrowly, limiting the service to people “located in states in which we offer the Service.” The two differ and no state list is published, so confirm yours as you search. The age floor is 18.

How fast. The menopause page promises “See your provider as soon as today,” the homepage advertises “Book same-day care with board-certified providers,” and booking runs 24/7. Where a prescription follows, the page lists “Same-day prescriptions” to a local pharmacy — so on Sesame’s own account, appointment and filled prescription can land on one day.

Visit format. Menopause care is video plus messaging: visits “as needed with your provider” and “Unlimited messaging” in between. The menopause page describes video only, so ask whether in-person hormone visits are bookable near you.

The cancellation terms are better than most in cash-pay telehealth, and they are numbers rather than discretion. The Terms of Service say Sesame “will honor a full refund for any of our visits when cancelled within the following time constraints” — then set them out: “Virtual visits: cancel up to 3 hours before the scheduled visit; In-person visits: cancel up to 24 hours before the scheduled visit.”

Three hours is a short leash for the company and a generous one for the patient: a same-day appointment you can no longer make is still refundable for most of the morning. The counterpart is stated just as plainly — “We are unable to offer refunds for the following: No-shows or missed appointments.” Cancel rather than simply not appearing.

Subscriptions and refills. Membership runs until you stop it: “You may cancel your subscription to Membership Services at any time up to forty-eight (48) hours before the applicable renewal processing date.” Refills are looser — “refills can be cancelled at any time if they have not been processed for delivery.” Which of those clauses governs the monthly menopause plan is not stated, so ask before the first charge. And membership is a discount, not coverage: “You cannot combine Sesame Membership with insurance or Medicare.”

Trustpilot, read September 18, 2026: 4.6 out of 5 from 4,441 reviews, 85% five-star against 11% one-star, with Trustpilot recording replies to 99% of negative reviews. Sesame’s own pages advertise “4.5” on Trustpilot; the two differ.

BBB, read the same day: a rating of A+, a BBB Accredited Business since December 27, 2022, with a business start date of January 1, 2018. It records 118 complaints over three years, 96 answered and 22 resolved. A separate BBB customer-review average is 3.71 out of 5 from 88 reviews — lower than Trustpilot, on a far smaller sample.

Apps, read the same day: the Apple App Store listing for “Sesame: Telehealth Care & More” shows 4.9 out of 5 from “10K Ratings.” Google Play shows 4.8 at the top of its page and 4.7 in its reviews section — two figures that do not match.

Regulatory record. No FDA or FTC action against Sesame was located in official sources. That carries an honest limit: our search budget ran out before a targeted search of the FTC’s own site could be completed, so read it as none located rather than as confirmation that none exists.

• Which menopause price applies today — $99 a month, $49 a month, or a single booked visit?
• Which cancellation clause covers the monthly menopause plan?

Compare options on our menopause clinic hub: Midi Health bills insurance, Winona runs a subscription. See also the telehealth glossary and how we review.